Manchester United have faced a hammer blow ahead of their Premier League clash with Leeds United as three of their main players have been ruled out of the fixture, manager Erik ten Hag confirmed.
Ten Hag revealed that Brazilian star Antony has joined the expanding list of injured players and has been ruled out due to injury.
Meanwhile, the Dutch coach also confirmed that Scott McTominay and Anthony Martial are still not ready to make their comebacks.
Christian Eriksen and Donny van de Beek are already out due to long-term injuries, and Casmeiro has begun serving a three-match suspension.
Casmeiro was given a straight red card on Saturday after grabbing Crystal Palace's Will Hughes by the throat.
"They are not involved tomorrow and the same with Antony, also not available tomorrow, so we have to sort it out," he remarked on Tuesday when discussing Martial and McTominay
"I always have to play with the players who are available and we have a squad, we have many good players in our squad who are also not playing in the starting XI and I have to do it.
"After a game, I can't say Casemiro is not there, Anthony Martial is not there, we have to win, this squad all players in are Man United capable, we have to win all the games."
However, despite claiming that Casemiro's red card is not the right decision, Ten Hag said that the Red Devils will not appeal to overturn the ban on Casemiro.
"Consider, yeah, still it's for me, not the right decision, but I don't think we have a chance in a legal process," he said.
Ten Hag's team is in fantastic form, having won five of their last seven league games since the post-World Cup resumption as they are in the Carabao Cup final and the fifth round of the FA Cup.
However, they have recently been plagued by injuries.
The 53-year-old opposed the sacking of Jesse Marsch by Leeds United on Monday.
"It's always sad if a manager, a colleague, gets sacked. So, in general, I don't believe in it that you sack a manager and get better results. Most of the time it doesn't work.
"Let the manager finish their work and make a good evaluation. But the pressure is high with decision makers at football clubs and they turn. But if you see the facts, most of the time it doesn't work out well."
The 13-time Premier League champions will take on Leeds at 01:00 am (PST).